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Overview:
There are 10 differences and 7 similarities between Spironolactone, Losartan
| Basic Medical Information |
| Common Brand Name |
| Aldactone |
Cozaar |
| Drug Class |
| Diuretics |
Angiotensin-receptor Blockers |
| Legal Status |
| Pom (uk), Rx-only (us) |
Rx -only |
| Possible Side Effects |
| Drowsiness, Lightheadedness, Stomach Upset, Diarrhea, Nausea, Vomiting, Headache, Muscle Spasms, Gynecomastia, Abdominal Pain, Skin Rashes |
Dizziness, Lightheadedness, Fainting, Irregular Heartbeat, Skin Rashes, Swelling, Difficulty Breathing |
| Precautions & Contraindications |
| Allergies, Kidney Disease, Liver Disease, Hyperkalemia, Pregnant, Breastfeeding |
Heart Disease, Cirrhosis, Kidney Disease, Diabetes, Allergies, Pregnant, Breastfeeding, Dialysis |
| Excretion |
| Urine, Biliary |
Renal, Biliary |
|
| Dosage, Usage and Forms |
| Route of Administration |
| Oral |
Oral |
| Dosage |
| 25 Mg |
50 Mg |
| Maximum daily dose |
| 100 mg |
100 mg |
| Forms |
| Tablet |
Tablet |
| Tablet Formulations |
| 25 Mg, 50 Mg, 100 Mg |
25 Mg, 50 Mg, 100 Mg |
| Chemical Data |
| Molecular mass (g/mol) |
| 416.57 g/mol |
422.91 g/mol |
| Half Life (hours) |
| 2 |
2 |
| Chemicals |
| Carbon, Hydrogen, Oxygen, Chlorine |
Carbon, Hydrogen, Nitrogen, Oxygen, Chlorine |
| Formula |
| C24h32o4s |
C22h23cln6o |
| Melting Point (C) |
| 134.5 C |
184 C |
| Phase (solid/liquid) |
| Solid |
Solid |